More specifically, the logistic EuroSCORE I does not include the patient factor diabetes, whereas the Society of Thoracic Surgery (STS) Score utilizes the patient factor diabetes, independently of the applied therapy; in the EuroSCORE II, DM on insulin is a patient-related factor considered to have satisfactory performance in predicting perioperative as well as 30-day mortality [20–22]. The gene discussed is INS; the disease is diabetes mellitus.