TRIM45 and neoplasm: On the other side, TRIMs like TRIM2 [86], TRIM3 [87,88], TRIM15 [89,90], TRIM26 [91], TRIM36 [92] TRIM45 [93], TRIM50 [94], TRIM58 [95,96], and TRIM62 [97] exert a tumor suppressor role, inhibiting cell proliferation and migration as well as promoting apoptosis.