HRAS and breast cancer: We also characterized Class IIa Hdac expression in several genetically engineered mouse models (GEMMs) of BC, including the UpkII-Hras*Q61L/WT, UpkII-Simian virus 40 large T antigen (SV40T), and UpkII-SV40T/ Hras*Q61L/WT [42,43].