In general, more proinflamatory cytokines (GM-CSF (granulocyte-macrophage colony stimulating factor), TNF-α, TGF-β-1 (transforming growth factor), IL-1β, IL-6, IL-17) and chemokines (chemokine C-X-C motif ligand (CXCL)9, CXCL10, CXCL11), reactive oxygen intermediate, chitotriosidase, angiotensin convertase enzyme and serum amyloid A have been observed among sarcoidosis patients. The gene discussed is TNF; the disease is sarcoidosis.