PLK4 and cancer: The results revealed POLQ overexpression (significant difference: 16/17 (94.1%)), PLK4 overexpression (significant difference: 15/17 (88.2%)), and a significant positive correlation between POLQ and PLK4 expression (17/17 (100%)) in the cancer types (Figure 6c, Supplementary Figure S3), suggesting that POLQ and PLK4 are concurrently overexpressed in diverse types of human cancers.