Genes such as LAMA4 [111], LAMA5 [112], and C1QTNF6 [113] were involved in angiogenesis in many cancer types such as renal cell carcinoma, colorectal cancer, and hepatocellular carcinoma, but these genes may be linked with angiogenesis in GBM. This evidence concerns the gene LAMA5 and hereditary clear cell renal cell carcinoma.