High expression of genes such as RPL36A, AP1S1, MRPL35, AKAP12, SHC1, ERBB2, PDLIM7, PCSK5, and MUC1 were linked with GBM, while low expression of genes such as ALPL was linked with the pathogenesis of GBM. The gene discussed is AP1S1; the disease is glioblastoma.