In NAFLD, cC16:1 and its elongation product, cC18:1, were increased due to the SREBP-1c-regulated increased Δ9 stearoyl-CoA desaturase 1 (SCD-1) activity [22], as seen in the alb-SREBP-1c model. The gene discussed is SREBF1; the disease is metabolic dysfunction-associated steatotic liver disease.