An indeed, 6q is the most affected chromosomal loss region in ovarian cancer [4], indicating LOH as driving event during the co-association network generation from expression data and sub-cluster identification of c1_496. The expression of the cluster c1_496 is negatively correlated to the Nectin 4 score indicating a positive correlation of 6q21 LOH frequency with Nectin 4 expression. This evidence concerns the gene NECTIN4 and ovarian cancer.