HCP5 and autoimmune disease: To better understand the genetics, molecular biology, and functions of HCP5, this paper reviewed the available data and literature on the genomic organization, structure, and function of the HCP5 gene (HLA complex P5 (non-protein coding), HGNC:21659) in health and disease (MIM:604676), particularly its association with autoimmune diseases, cancer, and infections by way of its endogenous interactions with miRNA and various gene targets.