On the other hand, HCP5 was predicted to be the regulated or child node with NLRC5, a member of the NOD-like receptor family that acts as a transcriptional activator of MHC class I genes [61,62,63], that was the parent or regulatory node in some gene expression experiments such as between adenocarcinoma and squamous cell carcinoma in non-small-cell lung carcinoma, breast cancer cell line profiles, non-Hodgkins lymphoma cell lines, complex genetic sarcomas, meningiomas, prostate cancer, and uveal melanoma primary tumors. The gene discussed is HCP5; the disease is squamous cell carcinoma.