DPYSL3 and autism: According to the prenatal sex steroid theory of autism, loss of the suppressive role of CRMP4 in Crmp4-KO mice in neuronal development may exaggerate the promotive effect of prenatal sex steroids, androgens and/or estrogens converted from androgens secreted from the testes, on neuronal network development, thereby resulting in male-biased ASD-like phenotypes.