CRP and rheumatoid arthritis: The low disease activity in our sample (e.g. median ESR: 14mm/h, median CRP: 0 mg/dl, median TJC: 0, median SJC: 0)–likely the result of adequate clinical care and sufficient access to effective bDMARDs–may accurately reflect treatment at German centres, but may also limit the generalizability of these results to large populations of patients with severe RA and patients with early or persistent RA.