Acquired monoclonal immunoglobulin light-chain amyloidosis (AL), the hereditary, transthyretin (TTR)-related form (ATTRm), and wild-type (non-mutant) TTR-related amyloidosis (ATTRwt) systemic “senile” amyloidosis account for more than 90% of all cardiac amyloidosis (CA) [2]. This evidence concerns the gene TTR and amyloidosis.