TAF1 and X-linked dystonia-parkinsonism: As an outstanding example, an unbiased de novo assembly using LRS (SMRT and synthetic longs reads with 10× Genomics) was important for the identification of SINE-VNTR-Alu insertion in TAF1, a newly discovered gene for X-linked Dystonia Parkinsonism (Aneichyk et al., 2018).