INS and hypertrophic cardiomyopathy: The top 10 were dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), calcium signaling pathway, arrhythmogenic right ventricular cardiomyopathy (ARVC), vascular smooth muscle contraction, cGMP-PKG signaling pathway, adrenergic signaling in cardiomyocytes, neuroactive ligand-receptor interaction, insulin secretion, and circadian entrainment (Figure 2D).