Moreover, we demonstrated that sVEGFR1-i13, a splice variant of the vascular endothelial growth factor receptor 1 (VEGFR1), is up-regulated in squamous lung carcinoma and promotes the proliferation and survival of tumor cells via a beta1 integrin-dependent autocrine loop (Abou Faycal et al., 2018). Here, FLT1 is linked to neoplasm.