The down-regulation of various circRNAs targeting ZEB1 (circ-ZEB1.5, circ_ZEB1.19, circ_ZEB1.17, and circ_ZEB1.33) increased the level of miR-200, which promoted tumor lung metastasis (Liu et al., 2016; Wang F. et al., 2016). Here, ZEB1 is linked to neoplasm.