To distinguish the roles of complement proteins and ACLA in thromboses and SLE, we segregated the study subjects according to their thrombosis and SLE status: thrombosis only (To), thrombotic SLE (TS), SLE only (So), and no thrombosis and no SLE (NTS) (Figure 1, Table 5). The gene discussed is VTN; the disease is systemic lupus erythematosus.