To determine the role of FKN in EMT and whether this was associated with signaling via the Wnt/β-catenin pathway in the renal fibrosis of MRL/lpr mice, we detected the levels of EMT and Wnt/β-catenin pathway components with qRT-PCR and western blot assays in all study groups. Here, CX3CL1 is linked to renal fibrosis.