As a warning signal during viral infections, different immune cellular pathogen recognition receptors, including toll-like receptors (TLR:2, 3, 4, 7, 8, and 9), nucleotide-binding oligomerization domain-like receptors, DNA receptors, and retinoic acid-inducible gene-1-like receptors, are able to sense a variety of pathogen-associated molecular patterns displayed by viruses (envelope glycoproteins, single and double-stranded RNA, and unmethylated CpG DNA), which stimulate transcription of IL-6 among other proinflammatory cytokines (Kawai and Akira, 2010; Tanaka et al., 2014). This evidence concerns the gene IL6 and viral infectious disease.