IL22 and digestive system infectious disorder: In mice, AhR has been shown to be indispensable for the development of IL-22+ NKp46+ innate lymphoid cells (ILCs) in the gut (Lee et al., 2011) and the importance of IL-22 in protection against intestinal infections (Guo et al., 2014) as well as lung tissue repair following severe influenza infection (Pociask et al., 2013).