NF-κB is necessary to promote the survival and proliferation of cancer cells by inducing the expression of anti-apoptotic genes (BCL-2) and activating cyclin, and activation of STAT3 in tumor cells enhances the ability of tumors to escape the immune system (Coussens and Werb, 2002; Jeyasuria et al., 2011). Here, STAT3 is linked to neoplasm.