HIF1A and Alzheimer disease: HIF1α expression was significantly different across LCL groups [F(2,44) = 11.99, p < 0.0001] due to higher expression in AD-N LCLs as compared to CNT [t(44) = 4.71, p < 0.0001] and AD-A [t(44) = 3.42, p = 0.001] LCLs.