SIRT1 and neoplasm: Recent studies confirmed that the expression of SIRT1, a class III histone deacetylase, regulates the migration of various cancer cells in vitro and tumor metastasis in vivo, including in hepatocellular carcinoma (Hao et al., 2014), colorectal cancer (Diesch et al., 2014), and gastric cancer (Zhang L. et al., 2013).