MAP1B and Alzheimer disease: This result confirmed that MAP1B, as a microtubule associated protein, had diverse involvement in neuron related biological processes (Ishitani et al., 2009; Maurin et al., 2009; Moritz et al., 2009; Villarroel-Campos and Gonzalez-Billault, 2014) and took important roles in the AD progression (Ulloa et al., 1994).