We found that the partners of MAP1B had diverse functions and many of them were associated with AD progression, such as intracellular signaling cascades (42 genes, p = 3.7e−4 and FDR = 0.2), regulation of apoptosis (18 genes, p = 3.4e−3 and FDR = 0.2), neuron and dendrite development (5 genes, p = 4.13e−3 and FDR = 0.3) and RNA metabolic process (19 genes, p = 4.71e−3 and FDR = 0.3). The gene discussed is MAP1B; the disease is Alzheimer disease.