ANK1 and Huntington disease: Beyond BD, bisulfite pyrosequencing demonstrates that ANK1 hypermethylation is not only observed in AD, but is also observed in Huntington’s disease and Parkinson’s disease, whereas samples with Vascular Dementia or Lewy bodies Dementia also demonstrated ANK1 hypermethylation, but only when they had coexisting AD-pathology (Smith et al., 2019).