Moreover, in a recent study a downregulation of 6 core autophagy genes (ULK 3, Atg2A, Atg4B, Atg5, Atg16L1, and histone deacetylase 6), and increased protein levels of ULK1, Beclin1, and AMBRA1 were detected in peripheral blood mononuclear cells (PBMCs) of PD patients (Miki et al., 2018). Here, BECN1 is linked to Parkinson disease.