To determine if simultaneous infection with ZIKV and DENV was accompanied by tissue damage, we examined the levels of Serum glutamic pyruvic transaminase (SGPT), Serum glutamic oxaloacetic transaminase (SGOT), Alkaline phosphatse, albumin and Creatine Phosphokinase (CPK), in serum samples that were collected longitudinally after infection and compared them to pre-infection values (Fig. 2a–f). The gene discussed is PIK3C2A; the disease is infection.