Genes encoding numerous NLR family proteins (NLRC4, NOD1, NOD2, NLRP1, NLRP3, NLRP12, and NAIP) and proinflammatory caspases/inflammasome adaptor molecules (PYCARD, CASP1, CASP4, and CASP5) were positively correlated with inflammasome complex genes in both LGG and GBM groups (Supplementary Fig. S1b,d,f) but not in normal brain (e.g., NLRC4, NLRP3, PYCARD, and CASP1; Supplementary Fig. S1b). This evidence concerns the gene CASP4 and glioblastoma.