KRAS and lung cancer: Using the same strategy, we further analyzed whether knocking down Aif by means of shRNA would affect the clonogenic potential and/or proliferation of additional human lung cancer cell lines, including five different KRAS-mutated cell lines (H460, H727, A427, H1650, and H358), and two lung cancer lines that are WT for KRAS (H1437 and H1975).