AIFM1 and lung adenocarcinoma: Transcriptome studies of both lung adenocarcinoma (Okayama dataset; GEO: GSE31210)20,21 and different lung cancer subtypes (Rosseaux dataset; GEO: GSE30219)22 demonstrated a significant upregulation of the AIF mRNA levels in lung cancer tissue compared to normal tissue (Fig. 8a).