On the basis of genetic analysis of the TTR gene, these patients with ATTRv amyloidosis had 15 different TTR mutations: Val30Met, Val28Ser, Val28Met, Gly47Arg, Thr49Ser, Thr49Ile, Gly53Glu, Thr60Ala, Glu61Lys, Lys80Arg, Gly83Arg, Glu89Gln, Ala97Gly, Tyr114Ser, and Tyr114Cys (Table 1). Here, TTR is linked to familial amyloid neuropathy.