Among them, hereditary renal hypouricemia (hRHUC) is a major type due to mutations of urate transporter URAT1 (encoded by SLC22A12 [OMIM *607096] and classified as hRHUC 1 [OMIM #220150]) and URATv1 (encoded by SLC2A9 [OMIM *606142] and classified as hRHUC 2 [OMIM #612076]) and is prone to exercise‐induced acute renal failure (EIARF) and urolithiasis especially in men (Ichida et al., 2008; Kaito et al., 2013). This evidence concerns the gene SLC22A12 and urolithiasis.