CD274 and neoplasm: For several decades, efforts have been made to improve the prognostic classification of STSs; different tumor cell‐intrinsic molecular parameters have been proposed, mainly related to cell cycle such as CINSARC (Chibon et al., 2010), as well as parameters related to immune microenvironment, such as PDL1/CD274 expression (Bertucci et al., 2017).