The decrease in IL-10 and TGF-β measured in the IEP group may play an important role in the resolution of the infection since the inflammatory cytokines IFN-γ and IL-12 were not modified in this group at the end of 12 weeks of infection in the systems stimulated by the parasitic antigen (popliteal lymph node) (Figures 5D,E). The gene discussed is IFNG; the disease is infection.