PLCL1 and nonpapillary renal cell carcinoma: As shown in Figure 1B, the heatmap indicated that the color of the expression profiles of these two genes in ccRCC tissues was colder‐colored than normal tissues, which meant that the messenger RNA (mRNA) levels of these two genes were both significantly lower in ccRCC tissues compared with normal tissues, Box‐plots also showed similar results, and we found that the low expression of PLCL1 was more pronounced in ccRCC.