In order to study pathogenesis, treatment and prophylaxis of campylobacteriosis in vertebrate hosts in more detail, we have established a murine C. jejuni infection model based on secondary abiotic IL-10−/− mice that not only allows for investigation of colonisation properties, but also reproducibly displays clinical symptoms resembling those of the compromized infected human host [28–30]. Here, IL10 is linked to campylobacteriosis.