ALS: Amyotrophic lateral sclerosis; FDA: Food and Drug Administration; FI:Fluorescence intensity; GABA: Gamma-Aminobutyric acid; GFAP: Glial FibrillaryAcidic Protein; HPLC: High performance liquid chromatography;L-Glu-L: Glutamate; MAP2: Microtubuleassociated protein 2; NeuN: Neuronal Nuclei; NMDA: N-methyl-D-aspartate;P. Here, MAP2 is linked to amyotrophic lateral sclerosis.