CD14 and systemic lupus erythematosus: A significant increase in HLA-DR−CD11b+CD33+ MDSCs, including both CD14+CD66b− monocytic and CD14−CD66b+ granulocytic MDSCs, was reported in the peripheral blood of patients with active SLE, and the frequency of these populations positively correlated with serum Arg1 activity, Th17 responses and lupus severity.