TAAR1 and Cognitive impairment: In addition, TAAR1 agonists are able to suppress the hyperlocomotion induced by the NMDA antagonist (Revel et al., 2011, 2013), decrease impulsive behavior in mice (Espinoza et al., 2015) and reverse the cognitive impairments in rats treated with the glutamate NMDA receptor antagonist (Revel et al., 2013).