MMP14 and breast carcinoma: Concerning the role of MT1-MMP in the regulation of collagen-induced apoptosis, we and others have previously shown that when expressed by luminal-like breast carcinoma, this metalloproteinase protects cells against collagen-induced apoptosis (Maquoi et al., 2012; Albrechtsen et al., 2013; Saby et al., 2018).