Importantly, short OS was correlated with large tumor diameter (HR 1.845, p = 0.012), poor differentiation (HR 1.978, p = 0.005), advanced T (HR 2.483, p = 0.034), advanced N (HR 2.039, p = 0.005), advanced M (HR 4.766, p < 0.001), advanced TNM stage (HR 2.205, p < 0.001), low CHIP expression (HR 0.497, p = 0.013), and high TRAF2 expression (HR 2.970, p < 0.001). The gene discussed is TRAF2; the disease is neoplasm.