AMPK signaling represses the activity of C/EBPβ not only in adipocytes but it can also suppress diverse functions driven by C/EBPβ, e.g., AMPK inhibits the C/EBPβ-driven ER stress in hepatoma cells [115] and cardiomyocytes [116]. The gene discussed is CEBPB; the disease is hepatocellular carcinoma.