ITGB3 and lupus nephritis: To assess how common uPAR-ITGB3 signaling activation is in podocytes in glomerular diseases, we searched the database of Nephroseq and found that uPAR is also upregulated in the glomeruli of diabetic nephropathy (Supplementary Fig. 6A), vasculitis (Supplementary Fig. 6B) and lupus nephritis (Supplementary Fig. 6C).