Using the first quartile of CRP as the referent, the mHR for ischemic stroke by second, third, and fourth quartiles were 1.19 (95% CI, 0.92-1.53), 1.05 (95% CI, 0.81-1.37), and 1.60 (95% CI, 1.23-2.08), respectively. The gene discussed is CRP; the disease is ischemic stroke.