We have previously used biomolecular-network reconstruction to identify T cell homing factors associated with survival in CRC and pinpointed specific chemokines (CX3CL1, CXCL9, CXCL10) and adhesion molecules (ICAM1, VCAM1, MADCAM1) associated with high densities of intratumoral T cell subsets [49]. Here, CX3CL1 is linked to colorectal carcinoma.