A natural extract from Centella asiatica, rich in ascorbic acid, asiatic acid, oleanolic acid, stevioside, stigmasterol and α-humulene protects diabetes tissues from stress via antioxidant and anti-inflammatory mechanisms eliciting brain reduced levels of malondialdehyde, TNF-α, IFN-γ, IL-4 or IL10 [127]. Here, TNF is linked to diabetes mellitus.