rs3803662 on 16q12, located close to TOX3 (TNRC9, CAGF9) and LOC643714 [39], has been identified as a breast cancer risk allele in various GWAS [11, 16, 22–24] and linked to both ER-positive [22, 40–43] and ER-negative primarily postmenopausal breast cancer [44]. Here, TOX3 is linked to breast carcinoma.