Analyses of renal immune cells revealed that vehicle‐treated SLE mice had a significantly higher percentage of CD45R+ B cells (Fig. 5A) compared to control mice, and CYC treatment SLE mice had significant fewer CD45R+ B cells in the kidney compared to SLE vehicle mice (14.94 ± 1.77 vs. 35.48 ± 5.77%, P < 0.05). The gene discussed is PTPRC; the disease is systemic lupus erythematosus.