Indeed, defects in the androgen receptor gene in 46,XY individuals affect the androgen‐dependent male sexual development, leading to an androgenin sensitivity syndrome (AIS) (Quigley et al., 1995; Sultan et al., 2002).The resulting phenotype exhibit sa genetic makeup of a male with the physical traits of a female, as observed in the present case. This evidence concerns the gene AR and androgen insensitivity syndrome.