SDHB and gastrointestinal stromal tumor: Independently of the underlining molecular mechanism, SDH‐deficient GISTs show unique clinical, pathological, and molecular features distinctive from SDH‐competent GIST.6 They usually occur in the stomach in young female patients, are often multifocal, show a distinctive multinodular/plexiform growth pattern, an epithelioid or mixed epithelioid/spindle cell morphology, and tend to metastasize to lymph nodes and liver.