Furthermore, SDHA mutations have been demonstrated in “apparently” sporadic adult gastric RTK‐WT GISTs.18, 19, 20 Analysis of large GIST sample collectives proposed that SDH deficiency is mutually exclusive to KIT/PDGFRA/BRAF/NF1/KRAS mutations.8, 21. This evidence concerns the gene SDHB and gastrointestinal stromal tumor.