Transcription of autophagic genes was not induced in CK1δ-, CK1α- and CK1α/δ-silenced MM cells (with the exception of LC3B whose expression was reduced in CK1δ silenced cells), suggesting that in these conditions FOXO3a likely does not localize in the nucleus (Fig. S9c). Here, FOXO3 is linked to Miyoshi myopathy.