Multivariate logistic regression analyses indicated that AP patients with a high ApoB/A1 ratio, expressed both as quartile and continuous variables, are prone to suffer a high risk of SAP, even after adjustment for age, sex, etiology of gallstones, BMI, smoking habit, WBC, neutrophil, lymphocyte, RBC, HGB, PLT, CRP, ALT, AST, LDH, glucose, ALB, amylase, BUN, calcium, TC, TG, HDL-C, LDL-C, ApoA1, or ApoB (Table 4, Model 1~4). This evidence concerns the gene APOA1 and alkaline phosphatase measurement.