Multivariate logistic regression analyses indicated that AP patients with a high ApoB/A1 ratio, expressed both as quartile and continuous variables, are prone to suffer a high risk of SAP, even after adjustment for age, sex, etiology of gallstones, BMI, smoking habit, WBC, neutrophil, lymphocyte, RBC, HGB, PLT, CRP, ALT, AST, LDH, glucose, ALB, amylase, BUN, calcium, TC, TG, HDL-C, LDL-C, ApoA1, or ApoB (Table 4, Model 1~4). The gene discussed is CYGB; the disease is alkaline phosphatase measurement.